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For all other topics, the terms “TRPC OR TRPV OR TRPM OR TRPA1 OR TRPML OR TRPP” were combined (AND) with a specific keyword related to the topic, as follows: Structure, functioning, exogenous/endogenous modulators, and signaling pathways: “structure OR modulation OR signaling.” Expression and functions in ocular structures: “Retina and retinal OR optic nerve OR pigment epithelium.” Ocular diseases: “Macular degeneration.” “Diabetic retinopathy,” “retina,” “methylglyoxal,” “glaucoma,” “intraocular pressure,” “retina” “retinitis pigmentosa,” “rd10,” “rd1.” For this review, we highlighted studies published in English in the last 5 years that brought new information to the subject up to publication
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Today, the FDA’s Pharmacy Compounding Advisory Committee voted to recommend BPC-157, TB-500, KPV, and MOTS-c for inclusion on the 503A Bulk Substances List